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Research · 24 Studies

BPC-157

We track 24 published, PubMed-indexed studies for BPC-157, spanning 2011 to 2026. The research below includes 20 reviews, 4 research articles.

WhatPeptidesDoUpdated Jun 2026Reviewed
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Key Takeaway

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.

20 Reviews
4 Research Articles

Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.

Review
Mayfield CK, Bolia IK, et al.|Am J Sports Med|2026
PubMed · PMID 41476424DOI: 10.1177/03635465251357593

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.

Review
Rahman OF, Lee SJ, et al.|J Am Acad Orthop Surg Glob Res Rev|2026
PubMed · PMID 41490200DOI: 10.5435/JAAOSGlobal-D-25-00236

Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.

Review
Mendias CL, Awan TM|Sports Med|2026
PubMed · PMID 41966639DOI: 10.1007/s40279-026-02437-0

Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.

Review
Józwiak M, Bauer M, et al.|Pharmaceuticals (Basel)|2025
PubMed · PMID 40005999DOI: 10.3390/ph18020185

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.

Review
Vasireddi N, Hahamyan H, et al.|HSS J|2025
PubMed · PMID 40756949DOI: 10.1177/15563316251355551

Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.

Review
McGuire FP, Martinez R, et al.|Curr Rev Musculoskelet Med|2025
PubMed · PMID 40789979DOI: 10.1007/s12178-025-09990-7

Injectable Therapeutic Peptides-An Adjunct to Regenerative Medicine and Sports Performance?

Review
DeFoor MT, Dekker TJ|Arthroscopy|2025
PubMed · PMID 39265666DOI: 10.1016/j.arthro.2024.09.005

Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study.

Research Article
Lee E, Burgess K|Altern Ther Health Med|2025
PubMed · PMID 40131143

The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity.

Review
Sikiric P, Boban Blagaic A, et al.|Pharmaceuticals (Basel)|2024
PubMed · PMID 38675421DOI: 10.3390/ph17040461

Stable Gastric Pentadecapeptide BPC 157 and Intestinal Anastomoses Therapy in Rats-A Review.

Review
Bajramagic S, Sever M, et al.|Pharmaceuticals (Basel)|2024
PubMed · PMID 39204186DOI: 10.3390/ph17081081

Stable Gastric Pentadecapeptide BPC 157-Possible Novel Therapy of Glaucoma and Other Ocular Conditions.

Review
Sikiric P, Kokot A, et al.|Pharmaceuticals (Basel)|2023
PubMed · PMID 37513963DOI: 10.3390/ph16071052

Stable Gastric Pentadecapeptide BPC 157 May Recover Brain-Gut Axis and Gut-Brain Axis Function.

Review
Sikiric P, Gojkovic S, et al.|Pharmaceuticals (Basel)|2023
PubMed · PMID 37242459DOI: 10.3390/ph16050676

Stable Gastric Pentadecapeptide BPC 157: Prompt Particular Activation of Collateral Pathways.

Research Article
Sikiric P, Gojkovic S, et al.|Curr Med Chem|2023
PubMed · PMID 36200148DOI: 10.2174/0929867329666221005111553

Pentadecapeptide BPC 157 and the central nervous system.

Review
Vukojevic J, Milavić M, et al.|Neural Regen Res|2022
PubMed · PMID 34380875DOI: 10.4103/1673-5374.320969

Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle.

Review
Staresinic M, Japjec M, et al.|Biomedicines|2022
PubMed · PMID 36551977DOI: 10.3390/biomedicines10123221

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

Review
Seiwerth S, Milavic M, et al.|Front Pharmacol|2021
PubMed · PMID 34267654DOI: 10.3389/fphar.2021.627533

Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.

Research Article
Lee E, Padgett B|Altern Ther Health Med|2021
PubMed · PMID 34324435

Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy.

Review
Sikiric P, Drmic D, et al.|Curr Pharm Des|2020
PubMed · PMID 32329684DOI: 10.2174/1381612826666200424180139

Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.

Review
Gwyer D, Wragg NM, et al.|Cell Tissue Res|2019
PubMed · PMID 30915550DOI: 10.1007/s00441-019-03016-8

BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing.

Review
Seiwerth S, Rucman R, et al.|Curr Pharm Des|2018
PubMed · PMID 29998800DOI: 10.2174/1381612824666180712110447

Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing.

Review
Sikiric P, Rucman R, et al.|Curr Pharm Des|2018
PubMed · PMID 29879879DOI: 10.2174/1381612824666180608101119

Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications.

Review
Sikiric P, Seiwerth S, et al.|Curr Neuropharmacol|2016
PubMed · PMID 27138887DOI: 10.2174/1570159x13666160502153022

Stable gastric pentadecapeptide BPC 157-NO-system relation.

Review
Sikiric P, Seiwerth S, et al.|Curr Pharm Des|2014
PubMed · PMID 23755725DOI: 10.2174/13816128113190990411

The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.

Research Article
Chang CH, Tsai WC, et al.|J Appl Physiol (1985)|2011
PubMed · PMID 21030672DOI: 10.1152/japplphysiol.00945.2010
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