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Mazdutide Research & Studies

We track 20 published, PubMed-indexed studies for Mazdutide, spanning 2022 to 2026. The research below includes 6 meta-analysiss, 6 clinical trials, 8 reviews.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
6
Meta-Analysiss
6
Clinical Trials
8
Reviews

Comparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta-Analysis of Randomised Controlled Trials.

Meta-Analysis
Abulehia A, Ayesh H, et al.|Endocrinol Diabetes Metab|2026

Mazdutide versus Semaglutide for the treatment of type 2 diabetes and obesity: Rationale, design and baseline data of DREAMS-3 phase 3 trial.

Clinical Trial
Luo Y, Jiang H, et al.|Contemp Clin Trials|2026

Novel GLP-1-based Medications for Type 2 Diabetes and Obesity.

Review
Son JW, le Roux CW, et al.|Endocr Rev|2026

Obesity in China: current progress and future prospects.

Review
Pan XF, Fang ZZ, et al.|Lancet Diabetes Endocrinol|2026

Efficacy and Safety of Mazdutide in Managing Overweight and Obesity Among Non-Diabetic Adults: A Meta-Analysis of Randomised Controlled Trials.

Review
Azam MH, Azam MH, et al.|Diabetes Obes Metab|2026

Comparative efficacy of incretin drugs on glycemic control, body weight, and blood pressure in adults with overweight or obesity and with/without type 2 diabetes: a systematic review and network meta-analysis.

Meta-Analysis
Liu S, Hu J, et al.|Front Endocrinol (Lausanne)|2025

Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight.

Clinical Trial
Ji L, Jiang H, et al.|N Engl J Med|2025

Mazdutide reduces body weight in adults with overweight or obesity: A high-dose Phase 1 trial.

Clinical Trial
Bhattachar SN, Tham LS, et al.|Diabetes Obes Metab|2025

Mazdutide: First Approval.

Review
Shirley M|Drugs|2025

Emerging pharmacotherapies for obesity: A systematic review.

Review
Kokkorakis M, Chakhtoura M, et al.|Pharmacol Rev|2025

Multifunctional incretin peptides in therapies for type 2 diabetes, obesity and associated co-morbidities.

Review
Bailey CJ, Flatt PR, Conlon JM|Peptides|2025

Mazdutide Versus Dulaglutide for Weight Loss and Diabetes Management: Meta-Analysis of Randomized Clinical Trials.

Meta-Analysis
Ayesh H, Ayesh S, Niswender K|Am J Ther|2024

Efficacy and safety of Mazdutide on weight loss among diabetic and non-diabetic patients: a systematic review and meta-analysis of randomized controlled trials.

Meta-Analysis
Nalisa DL, Cuboia N, et al.|Front Endocrinol (Lausanne)|2024

Seven glucagon-like peptide-1 receptor agonists and polyagonists for weight loss in patients with obesity or overweight: an updated systematic review and network meta-analysis of randomized controlled trials.

Meta-Analysis
Xie Z, Zheng G, et al.|Metabolism|2024

Safety and efficacy of GLP-1 and glucagon receptor dual agonist for the treatment of type 2 diabetes and obesity: a systematic review and meta-analysis of randomized controlled trials.

Meta-Analysis
Deng B, Ruan T, et al.|Endocrine|2024

Efficacy and Safety of Mazdutide in Chinese Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial.

Clinical Trial
Zhang B, Cheng Z, et al.|Diabetes Care|2024

Oral glucagon-like peptide-1 receptor agonists and combinations of entero-pancreatic hormones as treatments for adults with type 2 diabetes: where are we now?

Review
Gogineni P, Melson E, et al.|Expert Opin Pharmacother|2024

Approved and Emerging Hormone-Based Anti-Obesity Medications: A Review Article.

Review
Sidrak WR, Kalra S, Kalhan A|Indian J Endocrinol Metab|2024

A phase 2 randomised controlled trial of mazdutide in Chinese overweight adults or adults with obesity.

Clinical Trial
Ji L, Jiang H, et al.|Nat Commun|2023

A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes.

Clinical Trial
Jiang H, Pang S, et al.|Nat Commun|2022