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Melanotan II Research & Studies

We track 20 published, PubMed-indexed studies for Melanotan II, spanning 1996 to 2026. The research below includes 10 research articles, 8 reviews, 2 clinical trials.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
10
Research Articles
8
Reviews
2
Clinical Trials

Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report.

Research Article
Bonchev A|Life (Basel)|2026

Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?

Research Article
Yassin Alsabbagh A, Bhujel N, Singh RP|Int J Oral Maxillofac Surg|2025

5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II.

Research Article
Todorovic M, Blanc A, et al.|Chemistry|2024

Melanotan-II reverses memory impairment induced by a short-term HF diet.

Research Article
Wekwejt P, Wojda U, Kiryk A|Biomed Pharmacother|2023

CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.

Research Article
Tomassi S, Dimmito MP, et al.|J Med Chem|2022

Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.

Research Article
Eliason NL, Martin L, et al.|Neuropeptides|2022

Role of Temozolomide Regimen on Survival Outcomes in Molecularly Stratified WHO Grade II Gliomas: A Systematic Review.

Review
Ghaffari-Rafi A, Ghaffari-Rafi S, Leon-Rojas J|Asian J Neurosurg|2021

Melanotan II User Experience: A Qualitative Study of Online Discussion Forums.

Research Article
Gilhooley E, Daly S, McKenna D|Dermatology|2021

Melanotan II, a melanocortin agonist, partially rescues the impaired thermogenic capacity of pituitary adenylate cyclase-activating polypeptide deficient mice.

Research Article
McMillan TR, Forster MAM, et al.|Exp Physiol|2021

LC-HRMS characterization of the skin pigmentation and sexual enhancers melanotan II and bremelanotide sold on the black market of performance and image enhancing drugs.

Research Article
Mestria S, Odoardi S, et al.|Drug Test Anal|2021

Melanotan Tanning Injection: A Rare Cause of Priapism.

Research Article
Mallory CW, Lopategui DM, Cordon BH|Sex Med|2021

Melanotan II: a possible cause of renal infarction: review of the literature and case report.

Review
Peters B, Hadimeri H, et al.|CEN Case Rep|2020

Effect of Treatment Modalities on Progression-Free Survival and Overall Survival in Molecularly Subtyped World Health Organization Grade II Diffuse Gliomas: A Systematic Review.

Review
Ghaffari-Rafi A, Samandouras G|World Neurosurg|2020

Melanotan-induced priapism: a hard-earned tan.

Review
Dreyer BA, Amer T, Fraser M|BMJ Case Rep|2019

Metallothionein in Brain Disorders.

Review
Juárez-Rebollar D, Rios C, et al.|Oxid Med Cell Longev|2017

Protective role of metallothionein in chemical and radiation carcinogenesis.

Review
Fujiwara Y, Satoh M|Curr Pharm Biotechnol|2013

A review of metallothionein isoforms and their role in pathophysiology.

Review
Thirumoorthy N, Shyam Sunder A, et al.|World J Surg Oncol|2011

Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II.

Clinical Trial
Wessells H, Levine N, et al.|Int J Impot Res|2000

Discovery and development of novel melanogenic drugs. Melanotan-I and -II.

Review
Hadley ME, Hruby VJ, et al.|Pharm Biotechnol|1998

Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study.

Clinical Trial
Dorr RT, Lines R, et al.|Life Sci|1996