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Retatrutide Research & Studies

We track 21 published, PubMed-indexed studies for Retatrutide, spanning 2023 to 2026. The research below includes 13 reviews, 3 meta-analysiss, 5 clinical trials.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
13
Reviews
3
Meta-Analysiss
5
Clinical Trials

Retatrutide in type 2 diabetes mellitus and obesity: an overview.

Review
Panou T, Gouveri E, et al.|Expert Rev Clin Pharmacol|2026

Efficacy and Safety of GLP-1 Receptor Agonists, Dual Agonists, and Retatrutide for Weight Loss in Adults With Overweight or Obesity: A Bayesian NMA.

Meta-Analysis
Sinha B, Ghosal S|Obesity (Silver Spring)|2025

Efficacy and safety of triple hormone receptor agonist retatrutide for the management of obesity: a systematic review and meta-analysis.

Meta-Analysis
Tewari J, Qidwai KA, et al.|Expert Rev Clin Pharmacol|2025

Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial.

Clinical Trial
Coskun T, Wu Q, et al.|Lancet Diabetes Endocrinol|2025

Retatrutide-A Game Changer in Obesity Pharmacotherapy.

Review
Katsi V, Koutsopoulos G, et al.|Biomolecules|2025

Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials.

Review
Abdrabou Abouelmagd A, Abdelrehim AM, et al.|Proc (Bayl Univ Med Cent)|2025

Efficacy and safety of retatrutide for the treatment of obesity: a systematic review of clinical trials.

Review
Misra S, Narayan RK, Kaur M|J Basic Clin Physiol Pharmacol|2025

Efficacy of Tirzepatide, Retatrutide, and Semaglutide for Weight Loss in Obese Individuals Without Diabetes.

Review
Olowo-Oribi BA, Salway RJ|Acad Emerg Med|2025

What is the pipeline for future medications for obesity?

Review
Melson E, Ashraf U, et al.|Int J Obes (Lond)|2025

Emerging pharmacotherapies for obesity: A systematic review.

Review
Kokkorakis M, Chakhtoura M, et al.|Pharmacol Rev|2025

Tirzepatide versus Semaglutide Once Weekly in Patients with Obesity or Overweight (SURMOUNT-5): a head-to-head comparison trial.

Clinical Trial
Rodriguez PJ, Goodwin B, et al.|N Engl J Med|2025

Comparative Meta-Analysis of Retatrutide Versus Placebo and Dulaglutide for Weight Loss and Diabetes Management: Insights From Clinical Trials.

Meta-Analysis
Ayesh H, Ayesh S, Niswender K|Am J Ther|2024

Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial.

Clinical Trial
Sanyal AJ, Kaplan LM, et al.|Nat Med|2024

The power of three: Retatrutide's role in modern obesity and diabetes therapy.

Review
Abdul-Rahman T, Roy P, et al.|Eur J Pharmacol|2024

Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta-analysis of randomized controlled trials.

Review
Pasqualotto E, Ferreira ROM, et al.|Metabol Open|2024

A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity.

Review
Kaur M, Misra S|Eur J Clin Pharmacol|2024

Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity.

Review
Drucker DJ|Diabetes Care|2024

Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?

Review
Locatelli JC, Costa JG, et al.|Diabetes Care|2024

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.

Clinical Trial
Jastreboff AM, Kaplan LM, et al.|N Engl J Med|2023

Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA.

Clinical Trial
Rosenstock J, Frias J, et al.|Lancet|2023

Retatrutide showing promise in obesity (and type 2 diabetes).

Review
Doggrell SA|Expert Opin Investig Drugs|2023