5-Amino-1MQ Research & Studies
We track 20 published, PubMed-indexed studies for 5-Amino-1MQ, spanning 2020 to 2025. The research below includes 12 reviews, 8 research articles.
These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
12
Reviews
8
Research Articles
Nicotinamide N-Methyltransferase (NNMT) and Liver Cancer: From Metabolic Networks to Therapeutic Targets.
ReviewLai SY, Zhu XJ, et al.|Biomolecules|2025
Nicotinamide N-methyltransferase as a potential therapeutic target for neurodegenerative disorders: Mechanisms, challenges, and future directions.
ReviewLiu A, Zhu XJ, et al.|Exp Neurol|2025
Nicotinamide N-Methyltransferase in Cardiovascular Diseases: Metabolic Regulator and Emerging Therapeutic Target.
ReviewJawaria, Zarlashat Y, et al.|Biomolecules|2025
Nicotinamide N-methyltransferase in cardiovascular Diseases: Mechanistic insights and therapeutic potential.
ReviewBi SZ, Sun WD, et al.|Eur J Med Chem|2025
NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity.
Research ArticleHeide J, Bilecz AJ, et al.|Nature|2025
NNMT promotes acquired EGFR-TKI resistance by forming EGR1 and lactate-mediated double positive feedback loops in non-small cell lung cancer.
Research ArticleDai J, Lu X, et al.|Mol Cancer|2025
Nicotinamide-N-methyltransferase inhibition improves cardiac function and structure in a heart failure with preserved ejection fraction mouse model.
Research ArticleLi S, Rodrigues PG, et al.|Pharmacol Res|2025
NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment.
Research ArticleGhezzi B, Fiorilla I, et al.|Cell Commun Signal|2025
Exploring NNMT: from metabolic pathways to therapeutic targets.
ReviewPark J, Shin EJ, et al.|Arch Pharm Res|2024
Nicotinamide N-methyltransferase (NNMT): A key enzyme in cancer metabolism and therapeutic target.
ReviewSun WD, Zhu XJ, et al.|Int Immunopharmacol|2024
Nicotinamide N-methyltransferase (NNMT): a novel therapeutic target for metabolic syndrome.
ReviewSun WD, Zhu XJ, et al.|Front Pharmacol|2024
Nicotinamide N-Methyltransferase (NNMT): A New Hope for Treating Aging and Age-Related Conditions.
ReviewLi JJ, Sun WD, et al.|Metabolites|2024
Gastric Cancer in the Era of Epigenetics.
ReviewChristodoulidis G, Koumarelas KE, et al.|Int J Mol Sci|2024
NAD(+) metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer.
Research ArticleYang M, Wang B, et al.|J Immunother Cancer|2024
Nicotinamide N -methyltransferase promotes M2 macrophage polarization by IL6 and MDSC conversion by GM-CSF in gallbladder carcinoma.
Research ArticleLi Y, Yang B, et al.|Hepatology|2023
NNMT-DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition.
Research ArticleWu C, Liu Y, et al.|Adv Sci (Weinh)|2022
Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target.
ReviewGao Y, Martin NI, van Haren MJ|Drug Discov Today|2021
Mechanisms and inhibitors of nicotinamide N-methyltransferase.
ReviewIyamu ID, Huang R|RSC Med Chem|2021
Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation.
ReviewRoberti A, Fernández AF, Fraga MF|Mol Metab|2021
ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development.
Research ArticleSong Q, Chen Y, et al.|J Hepatol|2020