5-Amino-1MQ
Small molecule blocking NNMT, an enzyme that slows metabolism. Increases NAD+ production and energy expenditure. Promotes fat loss and may fix metabolic issues.
Key Facts
- ClassificationCapsule — Blocks the NNMT enzyme to speed up metabolism and burn more fat. Evidence is almost entirely preclinical.
- Primary BenefitsFat Loss (5/10) · Longevity (4/10) · Muscle Growth (2/10)
- AdministrationOral
- Typical Dose50-100 mg by mouth twice daily. Cycle for 8-12 weeks.
- Evidence StrengthEmerging — 20 peer-reviewed studies referenced · Community sentiment 6/10
- Stacks Well WithAOD-9604, Tesamorelin, Semaglutide, Retatrutide
- Legal StatusResearch Use Only · not prescribable in US
Quick Facts
- From price
- $40
- Type
- capsule
- Administration
- Oral
- Evidence
- emerging
- Studies referenced
- 20
- Community sentiment
- 6/10
- Stacks with
- 5 peptides
- Regulatory
- Research Use Only
Top benefits
Dosing
50-100 mg by mouth twice daily. Cycle for 8-12 weeks.
Benefit Profile
| Vendor | Variant | Price | |
|---|---|---|---|
| Limitless Biotech | 30ct 50mg | $44.99 | Code: PSTACK10Buy |
| Swiss Chems ⚠ FDA warning letter received late 2024 | 60ct 50mg | $69.95 | |
| Amino Asylum ⚠ Reported federal raid in 2025 | 30ct 50mg | $39.99BEST |
Stacks Well With
AOD-9604
The fat-burning fragment of growth hormone (amino acids 176-191). Promotes fat breakdown without muscle or blood sugar effects. Note: a Phase IIb trial failed to show significant weight loss vs placebo.
Tesamorelin
FDA-approved GH booster for reducing visceral belly fat in HIV-associated lipodystrophy. Trials showed ~15-18% visceral fat reduction. Overall weight loss is modest vs GLP-1 agonists.
Semaglutide
Active ingredient in Ozempic/Wegovy. Mimics GLP-1 to signal fullness and slow gastric emptying. STEP trials showed 14.9% weight loss at 68 weeks.
Retatrutide
Next-gen triple agonist from Eli Lilly hitting GLP-1, GIP, and glucagon receptors. Phase 2 showed 24.2% weight loss at 48 weeks — highest of any incretin therapy. At low doses, optimizes metabolism without major weight loss.
MOTS-c
Mitochondrial DNA-encoded peptide that activates AMPK, improving insulin sensitivity, fat burning, and mimicking exercise at the cellular level. Stacks well with SS-31 and NAD+.
Related 🔥 Fat Loss Peptides
Other peptides strong in fat loss
Dual GLP-1/GIP drug (Mounjaro/Zepbound). Strongest weight loss peptide available.
CagriSema10/10Next-gen dual semaglutide + amylin analog with strongest weight loss data.
Survodutide9/10Dual GLP-1/glucagon weight loss peptide from Boehringer Ingelheim.
Mazdutide9/10Dual GLP-1/glucagon receptor drug with strong weight loss results.
Orforglipron9/10First oral non-peptide GLP-1 agonist in late-stage trials.
Liraglutide8/10First-gen GLP-1 drug (Saxenda/Victoza). Effective but weaker than semaglutide.