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DSIP (Delta Sleep-Inducing Peptide) Research & Studies

We track 20 published, PubMed-indexed studies for DSIP (Delta Sleep-Inducing Peptide), spanning 1981 to 2026. The research below includes 9 reviews, 5 research articles, 6 clinical trials.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
9
Reviews
5
Research Articles
6
Clinical Trials

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.

Review
Rahman OF, Lee SJ, Seeds WA|J Am Acad Orthop Surg Glob Res Rev|2026

Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models.

Research Article
Mu X, Qu L, et al.|Front Pharmacol|2024

Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke.

Research Article
Tukhovskaya EA, Ismailova AM, et al.|Molecules|2021

Phosphorylated delta sleep inducing peptide restores spatial memory and p-CREB expression by improving sleep architecture at high altitude.

Research Article
Roy K, Chauhan G, et al.|Life Sci|2018

Expression and Purification of Delta Sleep-Inducing Peptide Fused with Protein Transduction Domain and Human Serum Albumin in Pichia pastoris.

Research Article
Zhang XG, Wang WN, et al.|Protein Pept Lett|2017

Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress.

Research Article
Bobyntsev II, Kryukov AA, et al.|Bull Exp Biol Med|2016

Delta sleep-inducing peptide alters bispectral index, the electroencephalogram and heart rate variability when used as an adjunct to isoflurane anaesthesia.

Clinical Trial
Pomfrett CJ, Dolling S, et al.|Eur J Anaesthesiol|2009

Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?

Review
Gimble JM, Ptitsyn AA, et al.|Obes Rev|2009

[Endogenous anticonvulsants: neuropeptide Y and delta sleep inducing peptide].

Review
Stanojlović O, Hrncić D, Radosavljević T|Med Pregl|2008

Delta sleep-inducing peptide (DSIP): a still unresolved riddle.

Review
Kovalzon VM, Strekalova TV|J Neurochem|2006

Delta sleep-inducing peptide.

Review
Pollard BJ, Pomfrett CJ|Eur J Anaesthesiol|2001

Delta-sleep-inducing peptide does not affect CRH and meal-induced ACTH and cortisol secretion.

Clinical Trial
Späth-Schwalbe E, Schäfer A, et al.|Psychoneuroendocrinology|1995

[The delta sleep-inducing peptide and its role in modulating epileptic activity].

Review
Shandra AA, Godlevskiĭ LS, et al.|Fiziol Zh Im I M Sechenova|1993

Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study.

Clinical Trial
Bes F, Hofman W, et al.|Neuropsychobiology|1992

DSIP--a tool for investigating the sleep onset mechanism: a review.

Review
Yehuda S, Carasso RL|Int J Neurosci|1988

Study of delta sleep-inducing peptide efficacy in improving sleep on short-term administration to chronic insomniacs.

Clinical Trial
Monti JM, Debellis J, et al.|Int J Clin Pharmacol Res|1987

Delta-sleep-inducing peptide (DSIP): an update.

Review
Graf MV, Kastin AJ|Peptides|1986

DSIP in insomnia.

Clinical Trial
Schneider-Helmert D|Eur Neurol|1984

Delta-sleep-inducing peptide (DSIP): a review.

Review
Graf MV, Kastin AJ|Neurosci Biobehav Rev|1984

The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep.

Clinical Trial
Schneider-Helmert D, Schoenenberger GA|Experientia|1981