DSIP (Delta Sleep-Inducing Peptide)
Brain peptide that promotes deep delta-wave sleep. Normalizes disrupted sleep patterns and reduces stress without next-day grogginess.
Key Facts
- ClassificationDelta Sleep-Inducing Peptide is a nonapeptide that increases delta wave (Stage III/IV) activity without suppressing REM sleep.
- Primary BenefitsSleep (7/10) · Mood & Anxiety (5/10) · Longevity (3/10)
- AdministrationInjection, Intranasal
- Typical Dose100-200 mcg subq or nasal spray about 30 minutes before bed. Use 5 days on, 2 days off.
- Evidence StrengthModerate — 20 peer-reviewed studies referenced · Community sentiment 10/10
- Stacks Well WithEpithalon, Selank, MK-677, Pinealon
- Legal StatusResearch Use Only · not prescribable in US
Quick Facts
- From price
- $30
- Type
- peptide
- Administration
- Injection, Intranasal
- Evidence
- moderate
- Studies referenced
- 20
- Community sentiment
- 10/10
- Stacks with
- 4 peptides
- Regulatory
- Research Use Only
Top benefits
Week 1–2
Improved sleep onset and increased delta wave sleep within the first few nights. Reduced time to fall asleep. More restorative, deeper sleep cycles.
Week 3–6
Normalized sleep architecture. Reduced stress response and cortisol levels. Improved next-day energy and cognitive performance from better sleep quality.
Week 8+
Sustained sleep improvements. Stress resilience improved via HPA axis normalization. Some users report reduced chronic pain perception.
Common Side Effects
Scientific Overview
Delta Sleep-Inducing Peptide is a nonapeptide that increases delta wave (Stage III/IV) activity without suppressing REM sleep. Modulates serotonergic and GABAergic systems with stress-protective effects via HPA axis normalization. Exhibits opiate antagonist properties.
Dosing
100-200 mcg subq or nasal spray about 30 minutes before bed. Use 5 days on, 2 days off.
Reconstitution, storage, injection sites & timing
Benefit Profile
| Vendor | Variant | Price | |
|---|---|---|---|
| Limitless Biotech | 5mg | $38.99 | Code: PSTACK10Buy |
| Skye Peptides | 5mg | $34.99 | |
| Amino Asylum ⚠ Reported federal raid in 2025 | 5mg | $29.99BEST | |
| Peptide Sciences ✕ Announced voluntary shutdown — stock availability may be limited or unavailable. Pricing data may be outdated. | 5mg | $45.00 | Out of stock |
Stacks Well With
Epithalon (Epitalon)
Longevity peptide from the pineal gland. Activates telomerase to protect DNA caps and restores melatonin production. Russian studies showed 11-16% lifespan increase in animals.
Selank
Russian anxiolytic peptide working on GABA, serotonin, and enkephalin systems. Eases anxiety without sedation or dependence risk. Also boosts immunity. Decades of clinical use.
MK-677 (Ibutamoren)
Orally active ghrelin receptor agonist (not a peptide). Boosts growth hormone and IGF-1. Known for improving deep sleep, increasing appetite, and gradually improving body composition.
Pinealon
Three-amino-acid Khavinson bioregulator that enters cells and interacts with DNA to activate brain-protective protein production. Reduces brain cell death and enhances neuronal repair.
Related 😴 Sleep Peptides
Other peptides strong in sleep
Clean GH booster with minimal side effects. Often paired with CJC-1295.
Ipamorelin/CJC-1295 Blend7/10Pre-mixed combo of Ipamorelin + CJC-1295 for convenient GH boosting.
Sermorelin6/10One of the most commonly prescribed GH peptides. Natural 29-amino-acid GH releaser.