Research · 24 Studies
GHK-Cu (Copper Peptide)
We track 24 published, PubMed-indexed studies for GHK-Cu (Copper Peptide), spanning 1977 to 2026. The research below includes 8 reviews, 16 research articles.
WhatPeptidesDoUpdated Jun 2026Reviewed
Key Takeaway
These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
8 Reviews
16 Research Articles
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
ReviewRahman OF, Lee SJ, et al.|J Am Acad Orthop Surg Glob Res Rev|2026
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.
ReviewMayfield CK, Bolia IK, et al.|Am J Sports Med|2026
Glycyl-L-histidyl-L-lysine-Cu2(+) (GHK-Cu) Attenuates CuSO(4) or LPS induced-inflammation in Zebrafish larvae model.
Research ArticleHu J, Zhang C, et al.|Eur J Pharmacol|2026
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
ReviewMendias CL, Awan TM|Sports Med|2026
An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant.
Research ArticleHu D, Zhang X, et al.|Colloids Surf B Biointerfaces|2025
Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects.
Research ArticleGreco V, Lanza V, et al.|Bioconjug Chem|2025
Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?
ReviewOgórek K, Nowak K, et al.|Molecules|2025
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms.
Research ArticleMao S, Huang J, et al.|Front Pharmacol|2025
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective.
ReviewMortazavi SM, Mohammadi Vadoud SA, et al.|Bioimpacts|2024
The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6.
Research ArticleBian Y, Deng M, et al.|Redox Biol|2024
Glycyl-l-histidyl-l-lysine-Cu(2+) rescues cigarette smoking-induced skeletal muscle dysfunction via a sirtuin 1-dependent pathway.
Research ArticleDeng M, Zhang Q, et al.|J Cachexia Sarcopenia Muscle|2023
Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application.
Research ArticleDymek M, Olechowska K, et al.|Pharmaceutics|2023
Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex via activation of SIRT1 in airway epithelial cells.
Research ArticleZhang Q, Liu J, et al.|Biomed Pharmacother|2023
Phenothiazine-Based Cu(II)-Selective Fluorescent Sensor: GHK-Cu Sensing Applications.
Research ArticleSahu R, Yadav S, et al.|J Org Chem|2023
GHK peptide prevents sleep-deprived learning impairment in aging mice.
Research ArticleRosenfeld M, Nickel K, et al.|Aging Pathobiol Ther|2023
Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.
Research ArticleAn P, Zhang Z, et al.|Anal Chem|2023
Glycyl-L-histidyl-L-lysine-Cu(2+) attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway.
Research ArticleZhang Q, Yan L, et al.|Front Mol Biosci|2022
The potential of GHK as an anti-aging peptide.
Research ArticleDou Y, Lee A, et al.|Aging Pathobiol Ther|2020
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.
ReviewPickart L, Margolina A|Int J Mol Sci|2018
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration.
ReviewPickart L, Vasquez-Soltero JM, et al.|Biomed Res Int|2015
The human tri-peptide GHK and tissue remodeling.
ReviewPickart L|J Biomater Sci Polym Ed|2008
The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures.
Research ArticleSiméon A, Emonard H, et al.|Life Sci|2000
Effects of the tripeptide glycyl-L-histidyl-L-lysine copper complex on osteoblastic cell spreading, attachment and phenotype.
Research ArticleGodet D, Marie PJ|Cell Mol Biol (Noisy-le-grand)|1995
Growth-modulating serum tripeptide is glycyl-histidyl-lysine.
Research ArticleSchlesinger DH, Pickart L, et al.|Experientia|1977