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peptide

GHK-Cu (Copper Peptide)

moderateResearch Use OnlyInjectionTopical

A naturally occurring copper peptide your body already makes. Drives skin rejuvenation, wound healing, and anti-aging by boosting collagen and activating anti-aging genes.


Key facts
Classification
GHK-Cu is a naturally occurring copper-binding tripeptide that modulates expression of ~4,000 human genes.
Primary benefits
Skin & Hair (10/10) · Longevity (7/10) · Inflammation (7/10)
Administration
Injection, Topical
Doses studied
1-3 mg daily subq, or apply it directly to the skin as a topical. Cycle for 4-8 weeks.
Evidence strength
Moderate — 24 peer-reviewed studies
Stacks well with
BPC-157, TB-500, Epithalon, SS-31
Legal status
Research Use Only · not prescribable in US
Quick stats
Type
Peptide
Administration
Injection, Topical
Studies referenced
24
Stacks with
5 peptides
Regulatory
Research Use Only
Scientific overview

GHK-Cu is a naturally occurring copper-binding tripeptide that modulates expression of ~4,000 human genes. Upregulates collagen synthesis (COL1A1, COL3A1), stem cell markers, and antioxidant enzymes while suppressing inflammation-associated genes. Plasma levels decline from ~200 ng/mL at age 20 to ~80 ng/mL by age 60.

Goal coverage · GHK-Cu (Copper Peptide)
Skin & Hair10/10
Longevity7/10
🧊 Inflammation7/10
🩹 Injury Healing6/10
🫃 Gut Health3/10
FIG.1  Modeled goal coverage from reviewed studies. Score out of 10.
Medical oversight recommendedNot safe during pregnancy· 3 contraindications
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