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KPV Research & Studies

We track 20 published, PubMed-indexed studies for KPV, spanning 2000 to 2026. The research below includes 11 research articles, 8 reviews, 1 clinical trial.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
11
Research Articles
8
Reviews
1
Clinical Trial

NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.

Research Article
Zeng K, Zhu Y, et al.|Cell Death Differ|2026

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

Research Article
Cheng J, Wu P, et al.|Sci Adv|2026

Host defense peptides as a new drug lead to a strategy for inflammatory bowel disease.

Review
Rodrigues JM, Ferreira Leal AP, et al.|Drug Discov Today|2025

Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.

Review
Adnan SB, Maarof M, et al.|Int J Med Sci|2025

Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.

Research Article
Sung J, Ju SY, et al.|Tissue Cell|2025

KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy.

Research Article
Zhang L, Li D, et al.|Adv Healthc Mater|2024

PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS.

Research Article
Zhang D, Jiang L, et al.|Front Pharmacol|2024

A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment.

Research Article
Marotti V, Xu Y, et al.|Bioact Mater|2024

The Melanocortin System in Inflammatory Bowel Diseases: Insights into Its Mechanisms and Therapeutic Potentials.

Review
Gravina AG, Pellegrino R, et al.|Cells|2023

Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns.

Clinical Trial
Wu YW, Comstock BA, et al.|N Engl J Med|2022

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.

Research Article
Zhao Y, Xue P, et al.|Acta Biomater|2022

Skin-adaptive film dressing with smart-release of growth factors accelerated diabetic wound healing.

Research Article
Zhao Y, Huang L, et al.|Int J Biol Macromol|2022

Self-Cross-Linked Hydrogel of Cysteamine-Grafted γ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in Rats.

Research Article
Sun J, Xue P, et al.|ACS Biomater Sci Eng|2021

Novel anti-inflammatory and chondroprotective effects of the human melanocortin MC1 receptor agonist BMS-470539 dihydrochloride and human melanocortin MC3 receptor agonist PG-990 on lipopolysaccharide activated chondrocytes.

Research Article
Can VC, Locke IC, et al.|Eur J Pharmacol|2020

Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin.

Research Article
Pawar K, Kolli CS, et al.|J Pharm Sci|2017

Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore.

Review
Brzoska T, Böhm M, et al.|Adv Exp Med Biol|2010

Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases.

Review
Brzoska T, Luger TA, et al.|Endocr Rev|2008

New insights into the functions of alpha-MSH and related peptides in the immune system.

Review
Luger TA, Scholzen TE, et al.|Ann N Y Acad Sci|2003

The neuroimmunomodulatory peptide alpha-MSH.

Review
Ichiyama T, Sato S, et al.|Ann N Y Acad Sci|2000

The neuropeptide alpha-MSH in host defense.

Review
Catania A, Cutuli M, et al.|Ann N Y Acad Sci|2000