MOTS-c Research & Studies
We track 20 published, PubMed-indexed studies for MOTS-c, spanning 2020 to 2025. The research below includes 20 reviews.
These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
20
Reviews
MOTS-c in type 2 diabetes mellitus: From risk factors to cardiac complications and potential treatment.
ReviewFang T, Han JC, et al.|Life Sci|2025
The correlation between mitochondrial derived peptide (MDP) and metabolic states: a systematic review and meta-analysis.
ReviewZhou Q, Yin S, et al.|Diabetol Metab Syndr|2024
Mitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives.
ReviewKal S, Mahata S, et al.|Peptides|2024
MOTS-c Functionally Prevents Metabolic Disorders.
ReviewGao Y, Wei X, et al.|Metabolites|2023
MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation.
ReviewZheng Y, Wei Z, Wang T|Front Endocrinol (Lausanne)|2023
MOTS-c: A potential anti-pulmonary fibrosis factor derived by mitochondria.
ReviewZhang Z, Chen D, et al.|Mitochondrion|2023
Role of MOTS-c in the regulation of bone metabolism.
ReviewYi X, Hu G, et al.|Front Physiol|2023
Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases.
ReviewKong BS, Lee C, Cho YM|Diabetes Metab J|2023
Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging.
ReviewWan W, Zhang L, et al.|J Transl Med|2023
Mitochondrial stress and mitokines in aging.
ReviewBurtscher J, Soltany A, et al.|Aging Cell|2023
MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases.
ReviewMohtashami Z, Singh MK, et al.|Int J Mol Sci|2022
Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c).
ReviewYoon TK, Lee CH, et al.|Diabetes Metab J|2022
Regulation of PRKN-independent mitophagy.
ReviewTerešak P, Lapao A, et al.|Autophagy|2022
Role of Immuno-Inflammatory Signals in Liver Ischemia-Reperfusion Injury.
ReviewKaltenmeier C, Wang R, et al.|Cells|2022
Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases.
ReviewHazafa A, Batool A, et al.|Life Sci|2021
The emerging role of mitochondrial derived peptide humanin in the testis.
ReviewLue Y, Swerdloff R, et al.|Biochim Biophys Acta Gen Subj|2021
Mitochondrial-derived peptides and exercise.
ReviewWoodhead JST, Merry TL|Biochim Biophys Acta Gen Subj|2021
Mitochondrial-Derived Peptides in Diabetes and Its Complications.
ReviewWu Y, Sun L, et al.|Front Endocrinol (Lausanne)|2021
Role of humanin, a mitochondrial-derived peptide, in cardiovascular disorders.
ReviewRochette L, Meloux A, et al.|Arch Cardiovasc Dis|2020
Mitochondrial-derived peptides in energy metabolism.
ReviewMerry TL, Chan A, et al.|Am J Physiol Endocrinol Metab|2020