Research · 20 Studies
MOTS-c
We track 20 published, PubMed-indexed studies for MOTS-c, spanning 2020 to 2025. The research below includes 20 reviews.
WhatPeptidesDoUpdated Jun 2026Reviewed
Key Takeaway
These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
20 Reviews
MOTS-c in type 2 diabetes mellitus: From risk factors to cardiac complications and potential treatment.
ReviewFang T, Han JC, et al.|Life Sci|2025
The correlation between mitochondrial derived peptide (MDP) and metabolic states: a systematic review and meta-analysis.
ReviewZhou Q, Yin S, et al.|Diabetol Metab Syndr|2024
Mitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives.
ReviewKal S, Mahata S, et al.|Peptides|2024
MOTS-c Functionally Prevents Metabolic Disorders.
ReviewGao Y, Wei X, et al.|Metabolites|2023
MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation.
ReviewZheng Y, Wei Z, Wang T|Front Endocrinol (Lausanne)|2023
MOTS-c: A potential anti-pulmonary fibrosis factor derived by mitochondria.
ReviewZhang Z, Chen D, et al.|Mitochondrion|2023
Role of MOTS-c in the regulation of bone metabolism.
ReviewYi X, Hu G, et al.|Front Physiol|2023
Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases.
ReviewKong BS, Lee C, Cho YM|Diabetes Metab J|2023
Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging.
ReviewWan W, Zhang L, et al.|J Transl Med|2023
Mitochondrial stress and mitokines in aging.
ReviewBurtscher J, Soltany A, et al.|Aging Cell|2023
MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases.
ReviewMohtashami Z, Singh MK, et al.|Int J Mol Sci|2022
Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c).
ReviewYoon TK, Lee CH, et al.|Diabetes Metab J|2022
Regulation of PRKN-independent mitophagy.
ReviewTerešak P, Lapao A, et al.|Autophagy|2022
Role of Immuno-Inflammatory Signals in Liver Ischemia-Reperfusion Injury.
ReviewKaltenmeier C, Wang R, et al.|Cells|2022
Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases.
ReviewHazafa A, Batool A, et al.|Life Sci|2021
The emerging role of mitochondrial derived peptide humanin in the testis.
ReviewLue Y, Swerdloff R, et al.|Biochim Biophys Acta Gen Subj|2021
Mitochondrial-derived peptides and exercise.
ReviewWoodhead JST, Merry TL|Biochim Biophys Acta Gen Subj|2021
Mitochondrial-Derived Peptides in Diabetes and Its Complications.
ReviewWu Y, Sun L, et al.|Front Endocrinol (Lausanne)|2021
Role of humanin, a mitochondrial-derived peptide, in cardiovascular disorders.
ReviewRochette L, Meloux A, et al.|Arch Cardiovasc Dis|2020
Mitochondrial-derived peptides in energy metabolism.
ReviewMerry TL, Chan A, et al.|Am J Physiol Endocrinol Metab|2020