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NAD+ (Nicotinamide Adenine Dinucleotide) Research & Studies

We track 20 published, PubMed-indexed studies for NAD+ (Nicotinamide Adenine Dinucleotide), spanning 2020 to 2025. The research below includes 20 reviews.

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These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
20
Reviews

NAD(+) precursor supplementation in human ageing: clinical evidence and challenges.

Review
Vinten KT, Trętowicz MM, et al.|Nat Metab|2025
PubMed (PMID: 41083806)DOI: 10.1038/s42255-025-01387-7

NAD(+) Boosting Strategies.

Review
Rice J, Lautrup S, Fang EF|Subcell Biochem|2024
PubMed (PMID: 39693020)DOI: 10.1007/978-3-031-66768-8_4

Regulation of and challenges in targeting NAD(+) metabolism.

Review
Migaud ME, Ziegler M, Baur JA|Nat Rev Mol Cell Biol|2024
PubMed (PMID: 39026037)DOI: 10.1038/s41580-024-00752-w

Roles of NAD(+) in Health and Aging.

Review
Lautrup S, Hou Y, et al.|Cold Spring Harb Perspect Med|2024
PubMed (PMID: 37848251)DOI: 10.1101/cshperspect.a041193

The therapeutic perspective of NAD(+) precursors in age-related diseases.

Review
Iqbal T, Nakagawa T|Biochem Biophys Res Commun|2024
PubMed (PMID: 38340651)DOI: 10.1016/j.bbrc.2024.149590

NAD metabolism and heart failure: Mechanisms and therapeutic potentials.

Review
Walker MA, Tian R|J Mol Cell Cardiol|2024
PubMed (PMID: 39096536)DOI: 10.1016/j.yjmcc.2024.07.008

Targeting NAD(+) metabolism: dual roles in cancer treatment.

Review
Yong J, Cai S, Zeng Z|Front Immunol|2023
PubMed (PMID: 38116009)DOI: 10.3389/fimmu.2023.1269896

Defining NAD(P)(H) Catabolism.

Review
Dhuguru J, Dellinger RW, Migaud ME|Nutrients|2023
PubMed (PMID: 37447389)DOI: 10.3390/nu15133064

NAD(+)-Consuming Enzymes in Stem Cell Homeostasis.

Review
Ji X, Zheng M, et al.|Oxid Med Cell Longev|2023
PubMed (PMID: 36819783)DOI: 10.1155/2023/4985726

NAD(+) metabolism in peripheral neuropathic pain.

Review
Dai Y, Lin J, et al.|Neurochem Int|2022
PubMed (PMID: 36273706)DOI: 10.1016/j.neuint.2022.105435

NAD(+) in COVID-19 and viral infections.

Review
Zheng M, Schultz MB, Sinclair DA|Trends Immunol|2022
PubMed (PMID: 35221228)DOI: 10.1016/j.it.2022.02.001

NAD(+) metabolism and its roles in cellular processes during ageing.

Review
Covarrubias AJ, Perrone R, et al.|Nat Rev Mol Cell Biol|2021
PubMed (PMID: 33353981)DOI: 10.1038/s41580-020-00313-x

NAD(+) homeostasis in human health and disease.

Review
Zapata-Pérez R, Wanders RJA, et al.|EMBO Mol Med|2021
PubMed (PMID: 34041853)DOI: 10.15252/emmm.202113943

NAD(+) metabolism, stemness, the immune response, and cancer.

Review
Navas LE, Carnero A|Signal Transduct Target Ther|2021
PubMed (PMID: 33384409)DOI: 10.1038/s41392-020-00354-w

Evolving concepts in NAD(+) metabolism.

Review
Chini CCS, Zeidler JD, et al.|Cell Metab|2021
PubMed (PMID: 33930322)DOI: 10.1016/j.cmet.2021.04.003

Role of NAD(+) in regulating cellular and metabolic signaling pathways.

Review
Amjad S, Nisar S, et al.|Mol Metab|2021
PubMed (PMID: 33609766)DOI: 10.1016/j.molmet.2021.101195

NAD(+) and cardiovascular diseases.

Review
Lin Q, Zuo W, et al.|Clin Chim Acta|2021
PubMed (PMID: 33485900)DOI: 10.1016/j.cca.2021.01.012

NAD(+) homeostasis in health and disease.

Review
Katsyuba E, Romani M, et al.|Nat Metab|2020
PubMed (PMID: 32694684)DOI: 10.1038/s42255-019-0161-5

NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.

Review
Braidy N, Liu Y|Exp Gerontol|2020
PubMed (PMID: 31917996)DOI: 10.1016/j.exger.2020.110831

NAD(+) Metabolism and Regulation: Lessons From Yeast.

Review
Croft T, Venkatakrishnan P, Lin SJ|Biomolecules|2020
PubMed (PMID: 32092906)DOI: 10.3390/biom10020330
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