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PE-22-28 Research & Studies

We track 21 published, PubMed-indexed studies for PE-22-28, spanning 2010 to 2025. The research below includes 20 research articles, 1 review.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
20
Research Articles
1
Review

A PEDF-Derived Short Peptide Prevents Sodium Iodate-Induced Retinal Degeneration in Rats by Activating the SLC7A11/GSH/GPX4 Pathway in the RPE Cells.

Research Article
Ho TC, Tsai SH, et al.|J Cell Mol Med|2025

Proteomic profiling of adipose-derived mesenchymal stromal cell response to novel compounds targeting the Laminin Receptor - PEDF interaction.

Research Article
Figueiredo ML, Figueiredo Neto M, et al.|Biochem Biophys Rep|2025

Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review.

Review
Jakobsen TS, Adsersen RL, et al.|Invest Ophthalmol Vis Sci|2024

PEDF-derived peptide protects against Amyloid-β toxicity in vitro and prevents retinal dysfunction in rats.

Research Article
Qarawani A, Naaman E, et al.|Exp Eye Res|2024

Corrigendum to "PEDF and PEDF-derived peptide 44mer inhibit oxygen-glucose deprivation-induced oxidative stress through upregulating PPARγ via PEDF-R in H9c2 cells" [Biochem. Biophys. Res. Commun. 473 (3) (2016) 482-488].

Research Article
Zhuang W, Zhang H, et al.|Biochem Biophys Res Commun|2023

A short peptide derived from pigment epithelial-derived factor exhibits an angioinhibitory effect.

Research Article
Ho TC, Yeh SI, et al.|BMC Ophthalmol|2022

The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation.

Research Article
Ho TC, Fan NW, et al.|Transl Vis Sci Technol|2022

Exploration of novel anti-angiogenic PEDF-derived peptides with improved activitives by inhibiting proliferation, suppressing migration, and inducing 67LR internalization.

Research Article
Shi W, Li J, et al.|Bioorg Chem|2021

Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy.

Research Article
Sheibani N, Zaitoun IS, et al.|Exp Eye Res|2020

PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells.

Research Article
Ho TC, Tsai SH, et al.|Stem Cell Res Ther|2019

Novel anti-angiogenic PEDF-derived small peptides mitigate choroidal neovascularization.

Research Article
Sheibani N, Wang S, et al.|Exp Eye Res|2019

Pigment epithelium-derived factor peptide reverses mouse age-related meibomian gland atrophy.

Research Article
Fan NW, Ho TC, et al.|Exp Eye Res|2019

Pedf derived peptides affect colorectal cancer cell lines resistance and tumour re-growth capacity.

Research Article
Honrubia-Gómez P, López-Garrido MP, et al.|Oncotarget|2019

Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity.

Research Article
Djillani A, Pietri M, et al.|Front Pharmacol|2017

Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation.

Research Article
Eichler W, Savković-Cvijić H, et al.|Cell Physiol Biochem|2017

Protective Role of PEDF-Derived Synthetic Peptide Against Experimental Diabetic Nephropathy.

Research Article
Ishibashi Y, Matsui T, et al.|Horm Metab Res|2016

PEDF and PEDF-derived peptide 44mer inhibit oxygen-glucose deprivation-induced oxidative stress through upregulating PPARγ via PEDF-R in H9c2 cells.

Research Article
Zhuang W, Zhang H, et al.|Biochem Biophys Res Commun|2016

PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL.

Research Article
Zhang H, Sun T, et al.|J Transl Med|2015

PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells.

Research Article
Ho TC, Chiang YP, et al.|Am J Physiol Cell Physiol|2015

Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/β-catenin Signaling in the Liver.

Research Article
Protiva P, Gong J, et al.|Cell Mol Gastroenterol Hepatol|2015

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

Research Article
Mazella J, Pétrault O, et al.|PLoS Biol|2010