Pentosan Polysulfate (PPS) Research & Studies
We track 20 published, PubMed-indexed studies for Pentosan Polysulfate (PPS), spanning 1994 to 2025. The research below includes 3 meta-analysiss, 11 reviews, 5 research articles, 1 clinical trial.
These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
3
Meta-Analysiss
11
Reviews
5
Research Articles
1
Clinical Trial
Risk and Dose-Response Relationship for Pentosan Polysulfate Sodium Maculopathy: A Systematic Review and Meta-Analysis.
Meta-AnalysisTao BK, Sawires K, et al.|Ophthalmol Retina|2025
Pentosan polysulfate maculopathy: clinical considerations, pathobiology, and causality.
ReviewHall BP, Shiromani S, et al.|Prog Retin Eye Res|2025
Pentosan polysulfate sodium maculopathy: Final analysis of a prospective cohort, updated review, and association with inflammatory bowel disease.
ReviewSantina A, Feo A, et al.|Surv Ophthalmol|2025
A review of the clinical efficacy and adverse effects of disease modifying osteoarthritic drugs (DMOADs) in dogs with special focus on glucosamine and pentosan polysulfate; do they work?
ReviewBwalya EC, Wijekoon HS, Okumura M|J Vet Med Sci|2025
Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?
ReviewProctor JG|Can J Urol|2023
Microperimetry Findings in Pentosan Polysulfate Maculopathy.
Research ArticleMost J, Kalaw FGP, et al.|Ophthalmol Retina|2023
Pentosan Polysulfate Maculopathy-We Need to Know More.
Research ArticleMaguire MG|JAMA Ophthalmol|2023
PENTOSAN POLYSULFATE SODIUM (ELMIRON) MACULOPATHY: A Genetic Perspective.
Research ArticleKalaw FGP, Ignacio JCI, et al.|Retina|2023
Pentosan polysulfate regulates hepcidin expression in native Mongolian horses.
Clinical TrialWijekoon S, Tsogbadrakh M, et al.|J Vet Med Sci|2022
Pentosan polysulfate maculopathy.
ReviewLindeke-Myers A, Hanif AM, Jain N|Surv Ophthalmol|2022
Pentosan Polysulfate, a Semisynthetic Heparinoid Disease-Modifying Osteoarthritic Drug with Roles in Intervertebral Disc Repair Biology Emulating the Stem Cell Instructive and Tissue Reparative Properties of Heparan Sulfate.
ReviewSmith MM, Hayes AJ, Melrose J|Stem Cells Dev|2022
Age-Related Macular Degeneration Masquerade: A Review of Pentosan Polysulfate Maculopathy and Implications for Clinical Practice.
ReviewMukhopadhyay C, Boyce TM, et al.|Asia Pac J Ophthalmol (Phila)|2022
Pentosan polysulfate maculopathy versus age-related macular degeneration: comparative assessment with multimodal imaging.
Research ArticleChristiansen JS, Barnes AC, et al.|Can J Ophthalmol|2022
Pentosan Polysulfate Maculopathy: What Urologists Should Know in 2020.
ReviewParedes Mogica JA, De EJB|Urology|2021
Update on maculopathy secondary to pentosan polysulfate toxicity.
ReviewAbou-Jaoude M, Fraser C, Maldonado RS|Curr Opin Ophthalmol|2021
Pentosan Polysulfate Maculopathy-Prescribers Should Be Aware.
Research ArticleYusuf IH, Charbel Issa P, Lotery AJ|JAMA Ophthalmol|2020
Efficacy of pentosan polysulfate for the treatment of interstitial cystitis/bladder pain syndrome: results of a systematic review of randomized controlled trials.
Meta-Analysisvan Ophoven A, Vonde K, et al.|Curr Med Res Opin|2019
Pentosan polysulfate: a review of its use in the relief of bladder pain or discomfort in interstitial cystitis.
ReviewAnderson VR, Perry CM|Drugs|2006
Efficacy of pentosan polysulfate in the treatment of interstitial cystitis: a meta-analysis.
Meta-AnalysisHwang P, Auclair B, et al.|Urology|1997
Pentosan polysulfate-induced thrombocytopenia and thrombosis.
ReviewTardy-Poncet B, Tardy B, et al.|Am J Hematol|1994