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capsule

Pentosan Polysulfate (PPS)

emergingResearch Use OnlyInjectionOral

Semi-synthetic polysaccharide (not a peptide) with anti-inflammatory and cartilage-protecting properties. FDA-approved for interstitial cystitis. Widely used for joint health.


Key facts
Classification
Capsule — Anti-inflammatory that protects cartilage and treats joint degeneration.
Primary benefits
Injury Healing (7/10) · Inflammation (7/10) · Gut Health (3/10)
Administration
Injection, Oral
Doses studied
2-3 mg per kg of body weight subq twice a week, or 100 mg by mouth 3 times daily. Cycle for 8-12 weeks.
Evidence strength
Emerging — 20 peer-reviewed studies
Stacks well with
BPC-157, TB-500
Legal status
Research Use Only · not prescribable in US
Quick stats
Type
Capsule
Administration
Injection, Oral
Studies referenced
20
Stacks with
2 peptides
Regulatory
Research Use Only
Goal coverage · Pentosan Polysulfate (PPS)
🩹 Injury Healing7/10
🧊 Inflammation7/10
🫃 Gut Health3/10
FIG.1  Modeled goal coverage from reviewed studies. Score out of 10.
From our network:Cornerstone Peptide