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Thymosin Alpha-1 Research & Studies

We track 20 published, PubMed-indexed studies for Thymosin Alpha-1, spanning 2008 to 2026. The research below includes 6 clinical trials, 6 meta-analysiss, 8 reviews.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
6
Clinical Trials
6
Meta-Analysiss
8
Reviews

Neoadjuvant immunochemotherapy plus thymalfasin in locally advanced gastric cancer: a prospective clinical trial.

Clinical Trial
Xu H, Li F, et al.|BMC Med|2026

Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis.

Meta-Analysis
Tian Y, Yao J, et al.|Front Immunol|2025

The Effect of Ulinastatin on Sepsis Outcomes: An Umbrella Review of Meta-Analysis.

Meta-Analysis
Cao S, Han P|Clin Ther|2025

The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial.

Clinical Trial
Wu J, Pei F, et al.|BMJ|2025

Aging and Thymosin Alpha-1.

Review
Simonova MA, Ivanov I, et al.|Int J Mol Sci|2025

Thymosin Alpha 1 Plus Routine Treatment for the Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.

Meta-Analysis
Cao A, Feng F, Zhou X|J Coll Physicians Surg Pak|2024

A Prospective and Randomized Control Study on Effects of Thymalfasin for Injection on Perioperative Immune Function and Long-term Prognosis of Patients with Colorectal Cancer.

Clinical Trial
Niu W, Li Z, et al.|Biotechnol Genet Eng Rev|2024

PD-1 inhibitor combined with SBRT, GM-CSF, and thymosin alpha-1 in metastatic breast cancer: A case report and literature review.

Review
Yu J, Wang Q, et al.|Medicine (Baltimore)|2024

Comprehensive Review of the Safety and Efficacy of Thymosin Alpha 1 in Human Clinical Trials.

Review
Dinetz E, Lee E|Altern Ther Health Med|2024

The efficacy of thymosin alpha-1 therapy in moderate to critical COVID-19 patients: a systematic review, meta-analysis, and meta-regression.

Meta-Analysis
Soeroto AY, Suryadinata H, et al.|Inflammopharmacology|2023

A pilot trial of Thymalfasin (Ta1) to prevent covid-19 infection and morbidities in renal dialysis patients: Preliminary report.

Clinical Trial
Tuthill CW, Awad A, et al.|Int Immunopharmacol|2023

The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis.

Meta-Analysis
Peng D, Xing HY, et al.|BMC Gastroenterol|2020

Thymosin alpha 1 in the prevention of infected pancreatic necrosis following acute necrotising pancreatitis (TRACE trial): protocol of a multicentre, randomised, double-blind, placebo-controlled, parallel-group trial.

Clinical Trial
Zhou J, Mao W, et al.|BMJ Open|2020

Thymosin alpha 1 treatment for patients with sepsis.

Review
Pei F, Guan X, Wu J|Expert Opin Biol Ther|2018

Serum thymosin alpha 1 levels in normal and pathological conditions.

Review
Pica F, Gaziano R, et al.|Expert Opin Biol Ther|2018

Thymosin alpha 1 and HIV-1: recent advances and future perspectives.

Review
Matteucci C, Grelli S, et al.|Future Microbiol|2017

Immune Modulation with Thymosin Alpha 1 Treatment.

Review
King R, Tuthill C|Vitam Horm|2016

A multicenter, randomized, observation-controlled clinical trial to evaluate the efficacy and safety of thymalfasin adjuvant therapy in patients with HBV-related HCC after curative resection - first announcement of the protocol.

Clinical Trial
Qiu SJ, Zhou ZG, et al.|Expert Opin Biol Ther|2015

Historical review of thymosin α 1 in infectious diseases.

Review
Camerini R, Garaci E|Expert Opin Biol Ther|2015

Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysis.

Meta-Analysis
Yang YF, Zhao W, et al.|Antiviral Res|2008