Thymosin Alpha-1
28-amino-acid immune peptide from thymus tissue. Strengthens T-cell maturation, boosts natural killer cells, and balances immune response. Tested in 30+ trials, approved in 35+ countries for hepatitis, HIV support, and infections. No serious side effects.
Key Facts
- ClassificationThymosin Alpha-1 is a 28-amino acid peptide from thymic tissue.
- Primary BenefitsImmune Support (10/10) · Longevity (5/10) · Inflammation (5/10)
- AdministrationInjection
- Typical Dose1.6-2 mg subq once or twice a week. Standard protocol is 1.6 mg twice weekly for 6-12+ months. You can increase frequency if you're fighting off an acute illness. Consistency matters more than timing.
- Evidence StrengthStrong — 20 peer-reviewed studies referenced · Community sentiment 8/10
- Stacks Well WithThymalin, BPC-157, LL-37, Selank
- Legal StatusResearch Use Only · not prescribable in US
Quick Facts
- From price
- $45
- Type
- peptide
- Administration
- Injection
- Evidence
- strong
- Studies referenced
- 20
- Community sentiment
- 8/10
- Stacks with
- 5 peptides
- Regulatory
- Research Use Only
Top benefits
Week 1–2
Enhanced innate immune surveillance. May notice fewer early cold/flu symptoms. Subtle improvement in energy if immune system was compromised.
Week 3–6
Measurably improved immune function — fewer infections, faster recovery from illness. Enhanced T-cell counts on bloodwork. Improved vaccine response.
Week 8+
Sustained immune optimization. Potential anti-tumor immune surveillance benefits. Improved recovery from chronic infections. Reduced autoimmune flare frequency in some users.
Common Side Effects
Scientific Overview
Thymosin Alpha-1 is a 28-amino acid peptide from thymic tissue. Enhances T-cell maturation, dendritic cell function, and NK cell activity. Modulates TLR2/5/9 signaling and promotes Th1 responses. Approved in 35+ countries for hepatitis B/C, with data spanning 3,000+ patients in controlled trials.
Dosing
1.6-2 mg subq once or twice a week. Standard protocol is 1.6 mg twice weekly for 6-12+ months. You can increase frequency if you're fighting off an acute illness. Consistency matters more than timing.
Reconstitution, storage, injection sites & timing
Benefit Profile
| Vendor | Variant | Price | |
|---|---|---|---|
| Limitless Biotech | 5mg | $52.99 | Code: PSTACK10Buy |
| Skye Peptides | 5mg | $54.99 | |
| Swiss Chems ⚠ FDA warning letter received late 2024 | 5mg | $54.95 | |
| Amino Asylum ⚠ Reported federal raid in 2025 | 5mg | $44.99BEST | |
| Peptide Sciences ✕ Announced voluntary shutdown — stock availability may be limited or unavailable. Pricing data may be outdated. | 5mg | $65.00 | Out of stock |
Stacks Well With
Thymalin
Derived from the thymus gland. Restores immune function and has shown life-extending properties by reactivating the aging immune system.
BPC-157
A healing compound from human gastric juice. The most extensively studied repair peptide in animal models, with strong preclinical data for tissue repair, gut restoration, and anti-inflammatory effects. Human clinical data remains limited.
LL-37
Your body's natural antibiotic peptide. Fights bacteria, viruses, and fungi, breaks up biofilms, and supports wound healing while modulating immune response.
Selank
Russian anxiolytic peptide working on GABA, serotonin, and enkephalin systems. Eases anxiety without sedation or dependence risk. Also boosts immunity. Decades of clinical use.
SS-31 (Elamipretide)
Engineered to target inner mitochondrial membrane via cardiolipin binding. Stabilizes cristae, improves ATP production, and reduces oxidative stress. FDA-approved for Barth syndrome (as Forzinity) — the first FDA-approved mitochondria-targeted therapy.
Compare
Despite sharing the "thymosin" name, Thymosin Alpha-1 (TA-1) and Thymosin Beta-4 (TB-4/TB-500) serve very different functions. TA-1 is an immune modulator, while TB-4 is a tissue repair peptide. They were both originally isolated from the thymus gland, but their biological roles are distinct.
LL-37 vs Thymosin Alpha-1LL-37 and Thymosin Alpha-1 are both immune peptides, but they operate on completely different aspects of immunity. LL-37 is an antimicrobial peptide that directly kills pathogens, while Thymosin Alpha-1 modulates the adaptive immune system by enhancing T-cell function. They represent innate vs. adaptive immunity, respectively.
Related 🛡️ Immune Support Peptides
Other peptides strong in immune support
Thymus hormone (requires zinc) that helps immune cells develop properly.
Vilon7/10Two-amino-acid immune peptide that supports thymus gland function.
VIP (Vasoactive Intestinal Peptide)7/10Widely used in mold illness and CIRS protocols. Powerful gut and immune modulator.
N-Acetyl Selank Amidate6/10Enhanced Selank with better stability. Reduces anxiety, boosts focus and mood.