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Tesofensine Research & Studies

We track 20 published, PubMed-indexed studies for Tesofensine, spanning 2007 to 2018. The research below includes 10 reviews, 9 clinical trials, 1 meta-analysis.

These summaries are for educational purposes. Research findings, particularly from preclinical studies, may not translate to human outcomes. Always consult a qualified healthcare provider before making decisions based on this information.
10
Reviews
9
Clinical Trials
1
Meta-Analysis

Centrally Acting Agents for Obesity: Past, Present, and Future.

Review
Coulter AA, Rebello CJ, Greenway FL|Drugs|2018

Future Pharmacotherapy for Obesity: New Anti-obesity Drugs on the Horizon.

Review
Srivastava G, Apovian C|Curr Obes Rep|2018

Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome.

Review
Maksimov ML, Svistunov AA, et al.|Curr Pharm Des|2016

New and emerging drug molecules against obesity.

Review
George M, Rajaram M, Shanmugam E|J Cardiovasc Pharmacol Ther|2014

Dopamine reuptake transporter (DAT) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaine.

Review
Heal DJ, Gosden J, Smith SL|Neuropharmacology|2014

The effect of tesofensine on appetite sensations.

Clinical Trial
Gilbert JA, Gasteyger C, et al.|Obesity (Silver Spring)|2012

Anti-obesity drugs: a review about their effects and their safety.

Review
Derosa G, Maffioli P|Expert Opin Drug Saf|2012

Neuropsychiatric adverse effects of centrally acting antiobesity drugs.

Review
Nathan PJ, O'Neill BV, et al.|CNS Neurosci Ther|2011

Serotonergic anti-obesity agents: past experience and future prospects.

Review
Halford JC, Boyland EJ, et al.|Drugs|2011

Subjective and objective effects of the novel triple reuptake inhibitor tesofensine in recreational stimulant users.

Clinical Trial
Schoedel KA, Meier D, et al.|Clin Pharmacol Ther|2010

Quantitative pharmacology approach in Alzheimer's disease: efficacy modeling of early clinical data to predict clinical outcome of tesofensine.

Clinical Trial
Lehr T, Staab A, et al.|AAPS J|2010

The effect of the triple monoamine reuptake inhibitor tesofensine on energy metabolism and appetite in overweight and moderately obese men.

Clinical Trial
Sjödin A, Gasteyger C, et al.|Int J Obes (Lond)|2010

Pharmacological management of appetite expression in obesity.

Review
Halford JC, Boyland EJ, et al.|Nat Rev Endocrinol|2010

[Recent progress and novel perspectives on obesity pharmacotherapy].

Review
Faria AM, Mancini MC, et al.|Arq Bras Endocrinol Metabol|2010

A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam.

Clinical Trial
Lehr T, Staab A, et al.|Clin Pharmacokinet|2009

Weight loss produced by tesofensine in patients with Parkinson's or Alzheimer's disease.

Meta-Analysis
Astrup A, Meier DH, et al.|Obesity (Silver Spring)|2008

Tesofensine (NS 2330), a monoamine reuptake inhibitor, in patients with advanced Parkinson disease and motor fluctuations: the ADVANS Study.

Clinical Trial
Rascol O, Poewe W, et al.|Arch Neurol|2008

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial.

Clinical Trial
Astrup A, Madsbad S, et al.|Lancet|2008

Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease.

Clinical Trial
Lehr T, Staab A, et al.|Br J Clin Pharmacol|2007

Randomized trial of the triple monoamine reuptake inhibitor NS 2330 (tesofensine) in early Parkinson's disease.

Clinical Trial
Hauser RA, Salin L, et al.|Mov Disord|2007