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peptide

TB-500 (Thymosin Beta-4)

moderateResearch Use OnlyInjection

Synthetic Thymosin Beta-4, a protein that drives cell migration and tissue repair. Promotes angiogenesis, reduces inflammation, and supports tissue remodeling body-wide. Popular for injury recovery.


Key facts
Classification
Thymosin Beta-4 is a 43-amino acid polypeptide that sequesters G-actin monomers, regulating actin polymerization for cell migration and tissue remodeling.
Primary benefits
Injury Healing (9/10) · Inflammation (8/10) · Muscle Growth (5/10)
Administration
Injection
Doses studied
Loading phase: 2-5 mg subq twice a week for 4 weeks. Then drop to 2 mg twice a week for maintenance.
Evidence strength
Moderate — 24 peer-reviewed studies
Stacks well with
BPC-157, GHK-Cu, SS-31, NAD+
Legal status
Research Use Only · not prescribable in US · WADA prohibited
Quick stats
Type
Peptide
Administration
Injection
Studies referenced
24
Stacks with
5 peptides
Regulatory
Research Use Only
Scientific overview

Thymosin Beta-4 is a 43-amino acid polypeptide that sequesters G-actin monomers, regulating actin polymerization for cell migration and tissue remodeling. Promotes angiogenesis through VEGF upregulation. Anti-inflammatory properties stem from NF-κB inhibition and reduced pro-inflammatory cytokines (IL-1β, TNF-α). Crosses the blood-brain barrier with demonstrated neuroprotective properties.

Goal coverage · TB-500 (Thymosin Beta-4)
🩹 Injury Healing9/10
🧊 Inflammation8/10
💪 Muscle Growth5/10
Skin & Hair5/10
🛡️ Immune Support3/10
FIG.1  Modeled goal coverage from reviewed studies. Score out of 10.
Medical oversight recommendedNot safe during pregnancy· 3 contraindications
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