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peptide

Selank

moderateResearch Use OnlyIntranasalInjection

Russian anxiolytic peptide working on GABA, serotonin, and enkephalin systems. Eases anxiety without sedation or dependence risk. Also boosts immunity. Decades of clinical use.


Key facts
Classification
Selank is a synthetic tuftsin analog with added Pro-Gly-Pro for stability.
Primary benefits
Mood & Anxiety (9/10) · Brain & Cognition (7/10) · Immune Support (5/10)
Administration
Intranasal, Injection
Doses studied
250-500 mcg subq or nasal spray, 3 times a week or as needed. No tolerance builds up, so no cycling needed. Can be mixed in the same syringe with Semax, SS-31, or NAD+.
Evidence strength
Moderate — 20 peer-reviewed studies
Stacks well with
Semax, Dihexa, SS-31, NAD+
Legal status
Research Use Only · not prescribable in US
Quick stats
Type
Peptide
Administration
Intranasal, Injection
Studies referenced
20
Stacks with
6 peptides
Regulatory
Research Use Only
Scientific overview

Selank is a synthetic tuftsin analog with added Pro-Gly-Pro for stability. Modulates GABAergic, serotonergic, and dopaminergic neurotransmission with benzodiazepine-comparable anxiolysis without sedation or dependence. Influences 36 genes including BDNF upregulation. Approved in Russia for GAD.

Goal coverage · Selank
😌 Mood & Anxiety9/10
🧠 Brain & Cognition7/10
🛡️ Immune Support5/10
😴 Sleep4/10
🧊 Inflammation3/10
FIG.1  Modeled goal coverage from reviewed studies. Score out of 10.
Medical oversight recommendedNot safe during pregnancy· 2 contraindications
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