CJC-1295 with DAC
Long-lasting growth hormone booster. The DAC modification keeps it active for days, producing steady GH elevation for muscle growth, fat loss, and recovery.
Key Facts
- ClassificationCJC-1295 with DAC is a synthetic GHRH analog modified with a maleimidopropionic acid linker that covalently binds serum albumin, extending half-life from ~7 minutes to 5-8 days.
- Primary BenefitsMuscle Growth (8/10) · Fat Loss (7/10) · Longevity (5/10)
- AdministrationInjection
- Typical Dose2 mg subq once a week. Cycle for 8-12 weeks.
- Evidence StrengthModerate — 20 peer-reviewed studies referenced · Community sentiment 7/10
- Stacks Well WithIpamorelin, MK-677, Sermorelin, Tesamorelin
- Legal StatusResearch Use Only · not prescribable in US · WADA prohibited
Quick Facts
- From price
- $28
- Type
- peptide
- Administration
- Injection
- Evidence
- moderate
- Studies referenced
- 20
- Community sentiment
- 7/10
- Stacks with
- 5 peptides
- Regulatory
- Research Use Only
Top benefits
Week 1–2
Increased deep sleep quality. Mild water retention. Slight increase in appetite. GH/IGF-1 levels begin rising steadily.
Week 3–6
Improved recovery from exercise. Fat loss begins, especially visceral fat. Skin quality improves. Sustained IGF-1 elevation measurable on labs.
Week 8+
Significant body recomposition — less fat, more lean mass. Joint and connective tissue repair. Improved sleep architecture. Hair and nail growth.
Common Side Effects
Scientific Overview
CJC-1295 with DAC is a synthetic GHRH analog modified with a maleimidopropionic acid linker that covalently binds serum albumin, extending half-life from ~7 minutes to 5-8 days. Stimulates pituitary somatotrophs for sustained GH pulsatility and IGF-1 elevation without disrupting natural secretory patterns.
Dosing
2 mg subq once a week. Cycle for 8-12 weeks.
Reconstitution, storage, injection sites & timing
Benefit Profile
| Vendor | Variant | Price | |
|---|---|---|---|
| Limitless Biotech | 2mg | $36.99 | Code: PSTACK10Buy |
| Skye Peptides | 2mg | $34.99 | |
| Skye Peptides | 5mg | $64.99 | |
| Swiss Chems ⚠ FDA warning letter received late 2024 | 2mg | $34.95 | |
| Amino Asylum ⚠ Reported federal raid in 2025 | 2mg | $27.99BEST | |
| Peptide Sciences ✕ Announced voluntary shutdown — stock availability may be limited or unavailable. Pricing data may be outdated. | 2mg | $39.00 | Out of stock |
Stacks Well With
Ipamorelin
One of the cleanest GH boosters. Stimulates growth hormone release without affecting cortisol or prolactin, meaning fewer side effects than other GH peptides.
MK-677 (Ibutamoren)
Orally active ghrelin receptor agonist (not a peptide). Boosts growth hormone and IGF-1. Known for improving deep sleep, increasing appetite, and gradually improving body composition.
Sermorelin
One of the most prescribed GH peptides. Copies the first 29 amino acids of natural GHRH, triggering physiological GH pulses from the pituitary.
Tesamorelin
FDA-approved GH booster for reducing visceral belly fat in HIV-associated lipodystrophy. Trials showed ~15-18% visceral fat reduction. Overall weight loss is modest vs GLP-1 agonists.
IGF-1 LR3
Modified IGF-1 with extended half-life. Can create new muscle cells (not just enlarge existing ones), making it one of the most potent muscle-building peptides.
Compare
CJC-1295 and Ipamorelin are both growth hormone secretagogues, but they work through different receptor pathways. CJC-1295 is a GHRH (growth hormone-releasing hormone) analog, while Ipamorelin is a growth hormone-releasing peptide (GHRP). They are frequently combined rather than used as alternatives.
MK-677 vs CJC-1295MK-677 (Ibutamoren) and CJC-1295 both elevate growth hormone levels, but through entirely different mechanisms and routes. MK-677 is technically not a peptide -- it's a non-peptide ghrelin mimetic taken orally. CJC-1295 is a GHRH analog that requires injection. This distinction significantly affects their use profiles.
CJC-1295 vs SermorelinCJC-1295 and Sermorelin are both GHRH analogs that stimulate growth hormone release through the same receptor pathway. The key difference is that Sermorelin was the first GHRH analog with decades of clinical use, while CJC-1295 is a newer modified version designed for a much longer half-life.
Related 💪 Muscle Growth Peptides
Other peptides strong in muscle growth
10x more potent IGF-1 variant with very short duration. Targets local muscle.
GHRP-28/10Stronger GH release than GHRP-6, with less appetite stimulation.
Follistatin 3448/10Blocks myostatin to remove the genetic cap on muscle growth.
Ipamorelin/CJC-1295 Blend8/10Pre-mixed combo of Ipamorelin + CJC-1295 for convenient GH boosting.
PEG-MGF (Mechano Growth Factor)8/10Long-lasting muscle growth factor released after exercise-induced damage.
CJC-1295 (no DAC) / Mod GRF 1-297/10Growth hormone releaser that mimics natural pulsatile GH patterns.