Tesamorelin
FDA-approved GH booster for reducing visceral belly fat in HIV-associated lipodystrophy. Trials showed ~15-18% visceral fat reduction. Overall weight loss is modest vs GLP-1 agonists.
Key Facts
- ClassificationTesamorelin is a 44-amino acid GHRH analog with trans-3-hexenoic acid modification.
- Primary BenefitsFat Loss (8/10) · Muscle Growth (6/10) · Longevity (4/10)
- AdministrationInjection
- Typical Dose2 mg subq daily, preferably before bed. Cycle for 12-26 weeks.
- Evidence StrengthStrong — 20 peer-reviewed studies referenced · Community sentiment 9/10
- Stacks Well WithAOD-9604, Ipamorelin
- Legal StatusFDA-Approved · prescription required · WADA prohibited
Quick Facts
- From price
- $35
- Type
- peptide
- Administration
- Injection
- Evidence
- strong
- Studies referenced
- 20
- Community sentiment
- 9/10
- Stacks with
- 2 peptides
- Regulatory
- FDA-Approved
Top benefits
Week 1–2
Subtle changes in body composition beginning. Improved sleep quality. Mild injection site reactions common. GH/IGF-1 levels starting to rise.
Week 3–6
Measurable reduction in visceral adipose tissue. Improved lipid panel markers. Better body composition visible. Enhanced recovery from physical activity.
Week 8+
Significant visceral fat reduction (15%+ in clinical trials). Improved triglyceride and cholesterol levels. Sustained GH optimization without insulin resistance.
Common Side Effects
Scientific Overview
Tesamorelin is a 44-amino acid GHRH analog with trans-3-hexenoic acid modification. FDA-approved for HIV-associated lipodystrophy with ~15% trunk fat reduction and improved lipid profiles. Maintains physiological GH pulsatility without GH-associated insulin resistance.
Dosing
2 mg subq daily, preferably before bed. Cycle for 12-26 weeks.
Reconstitution, storage, injection sites & timing
Benefit Profile
| Vendor | Variant | Price | |
|---|---|---|---|
| Limitless Biotech | 2mg | $44.99 | Code: PSTACK10Buy |
| Swiss Chems ⚠ FDA warning letter received late 2024 | 2mg | $42.95 | |
| Amino Asylum ⚠ Reported federal raid in 2025 | 2mg | $34.99BEST | |
| Peptide Sciences ✕ Announced voluntary shutdown — stock availability may be limited or unavailable. Pricing data may be outdated. | 2mg | $49.00 | Out of stock |
Stacks Well With
AOD-9604
The fat-burning fragment of growth hormone (amino acids 176-191). Promotes fat breakdown without muscle or blood sugar effects. Note: a Phase IIb trial failed to show significant weight loss vs placebo.
Ipamorelin
One of the cleanest GH boosters. Stimulates growth hormone release without affecting cortisol or prolactin, meaning fewer side effects than other GH peptides.
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