peptide
Ipamorelin
moderateResearch Use OnlyInjection
One of the cleanest GH boosters. Stimulates growth hormone release without affecting cortisol or prolactin, meaning fewer side effects than other GH peptides.
Key facts
- Classification
- Ipamorelin is a pentapeptide GHS that selectively activates GHSR-1a on pituitary somatotrophs.
- Primary benefits
- Muscle Growth (7/10) · Sleep (7/10) · Fat Loss (6/10)
- Administration
- Injection
- Doses studied
- 200-300 mcg subq 2-3 times daily, ideally before bed. Cycle for 8-12 weeks.
- Evidence strength
- Moderate — 20 peer-reviewed studies
- Stacks well with
- CJC-1295 with DAC, CJC-1295 (no DAC) / Mod GRF 1-29, MK-677, Sermorelin
- Legal status
- Research Use Only · not prescribable in US · WADA prohibited
Quick stats
- Type
- Peptide
- Administration
- Injection
- Studies referenced
- 20
- Stacks with
- 5 peptides
- Regulatory
- Research Use Only
Scientific overview
Ipamorelin is a pentapeptide GHS that selectively activates GHSR-1a on pituitary somatotrophs. Unlike GHRP-6 and GHRP-2, it does not significantly stimulate ACTH, cortisol, or prolactin, providing a cleaner GH-specific signal with dose-dependent release.
Goal coverage · Ipamorelin
💪 Muscle Growth7/10
😴 Sleep7/10
🔥 Fat Loss6/10
⏳ Longevity4/10
🩹 Injury Healing3/10
Medical oversight strongly recommendedNot safe during pregnancy· 4 contraindications