peptide
Oxytocin
strongFDA-Approved· RxIntranasalInjection
The bonding hormone released during social connection. Promotes trust, empathy, and closeness while reducing anxiety and cortisol.
Key facts
- Classification
- Oxytocin is a cyclic nonapeptide from hypothalamic nuclei.
- Primary benefits
- Mood & Anxiety (7/10) · Sleep (4/10) · Inflammation (2/10)
- Administration
- Intranasal, Injection
- Doses studied
- 10-24 IU as a nasal spray as needed, or 10-20 IU subq. Not meant for daily chronic use.
- Evidence strength
- Strong — 20 peer-reviewed studies
- Stacks well with
- Selank, DSIP
- Legal status
- FDA-Approved · prescription required
Quick stats
- Type
- Peptide
- Administration
- Intranasal, Injection
- Studies referenced
- 20
- Stacks with
- 2 peptides
- Regulatory
- FDA-Approved
Scientific overview
Oxytocin is a cyclic nonapeptide from hypothalamic nuclei. Beyond parturition and lactation, it modulates social cognition, pair bonding, and stress responses via OXTR signaling. Intranasal delivery achieves CNS penetration via olfactory/trigeminal pathways.
Goal coverage · Oxytocin
😌 Mood & Anxiety7/10
😴 Sleep4/10
🧊 Inflammation2/10
Medical oversight requiredNot safe during pregnancy· 4 contraindications