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🔥 Best Peptides for Fat Loss

Metabolic peptides target fat loss through appetite regulation, increased energy expenditure, and preferential visceral fat reduction. GLP-1 receptor agonists, growth hormone secretagogues, and mitochondrial enhancers each offer distinct mechanisms for improving body composition. Several compounds in this category have robust clinical trial data and FDA approval.

33
Peptides
17
Strong / Moderate
$20–$110
Price Range
🔥 Fat Loss Longevity

GLP-1 drug (Ozempic/Wegovy) that suppresses appetite and burns fat.

Fat Loss
10/10
Sentiment
10/10
from $85
Details →
🔥 Fat Loss Longevity

Dual GLP-1/GIP drug (Mounjaro/Zepbound). Strongest weight loss peptide available.

Fat Loss
10/10
Sentiment
9/10
from $110
Details →

Retatrutide

moderate
🔥 Fat Loss🧠 Brain & Cognition Longevity

Triple-action weight loss drug hitting GLP-1, GIP, and glucagon receptors.

Fat Loss
10/10
Sentiment
9/10
from $95
Details →

CagriSema

emerging
🔥 Fat Loss

Next-gen dual semaglutide + amylin analog with strongest weight loss data.

Fat Loss
10/10
Sentiment
7/10

Survodutide

emerging
🔥 Fat Loss🫃 Gut Health

Dual GLP-1/glucagon weight loss peptide from Boehringer Ingelheim.

Fat Loss
9/10
Sentiment
5/10
from $100
Details →

Mazdutide

emerging
🔥 Fat Loss

Dual GLP-1/glucagon receptor drug with strong weight loss results.

Fat Loss
9/10
Sentiment
10/10
from $95
Details →

Orforglipron

emerging
🔥 Fat Loss

First oral non-peptide GLP-1 agonist in late-stage trials.

Fat Loss
9/10
Sentiment
8/10
🔥 Fat Loss💪 Muscle Growth

FDA-approved GH booster that specifically reduces visceral belly fat.

Fat Loss
8/10
Sentiment
9/10
from $35
Details →

MOTS-c

emerging
🔥 Fat Loss Longevity

Mitochondrial peptide that mimics exercise benefits at the cellular level.

Fat Loss
8/10
Sentiment
9/10
from $53
Details →
🔥 Fat Loss

First-gen GLP-1 drug (Saxenda/Victoza). Effective but weaker than semaglutide.

Fat Loss
8/10
Sentiment
8/10
💪 Muscle Growth🔥 Fat Loss Longevity

Long-acting growth hormone booster that stays active for days.

Fat Loss
7/10
Sentiment
7/10
from $28
Details →
💪 Muscle Growth🔥 Fat Loss😴 Sleep

Pre-mixed combo of Ipamorelin + CJC-1295 for convenient GH boosting.

Fat Loss
7/10
Sentiment
9/10
from $45
Details →

Tesofensine

emerging
🔥 Fat Loss

Potent weight loss drug originally developed for neurological conditions.

Fat Loss
7/10
Sentiment
9/10
from $70
Details →

SLU-PP-332

anecdotal
🔥 Fat Loss💪 Muscle Growth Longevity

Exercise mimetic that activates endurance pathways without working out.

Fat Loss
7/10
Sentiment
8/10
from $70
Details →
💪 Muscle Growth🔥 Fat Loss

Growth hormone releaser that mimics natural pulsatile GH patterns.

Fat Loss
6/10
Sentiment
9/10
from $25
Details →

Ipamorelin

moderate
💪 Muscle Growth😴 Sleep🔥 Fat Loss

Clean GH booster with minimal side effects. Often paired with CJC-1295.

Fat Loss
6/10
Sentiment
8/10
from $25
Details →

AOD-9604

emerging
🔥 Fat Loss

The fat-burning fragment of growth hormone. No muscle or blood sugar effects.

Fat Loss
6/10
Sentiment
5/10
from $30
Details →
💪 Muscle Growth🔥 Fat Loss😴 Sleep

One of the most commonly prescribed GH peptides. Natural 29-amino-acid GH releaser.

Fat Loss
6/10
Sentiment
8/10
from $33
Details →

GHRP-2

moderate
💪 Muscle Growth🔥 Fat Loss😴 Sleep

Stronger GH release than GHRP-6, with less appetite stimulation.

Fat Loss
5/10
Sentiment
9/10
from $23
Details →

Hexarelin

moderate
💪 Muscle Growth🔥 Fat Loss🩹 Injury Healing

The most potent GH-releasing peptide. Produces the biggest GH spike but tolerance builds quickly.

Fat Loss
5/10
Sentiment
7/10
from $28
Details →
😴 Sleep💪 Muscle Growth🔥 Fat Loss

Oral GH booster (not a peptide). Raises growth hormone and IGF-1 levels.

Fat Loss
5/10
Sentiment
6/10
from $45
Details →

5-Amino-1MQ

emerging
🔥 Fat Loss

Blocks the NNMT enzyme to speed up metabolism and burn more fat. Evidence is almost entirely preclinical.

Fat Loss
5/10
Sentiment
6/10
from $40
Details →
💪 Muscle Growth🔥 Fat Loss

Blocks myostatin to remove the genetic cap on muscle growth.

Fat Loss
5/10
Sentiment
8/10
from $80
Details →
🔥 Fat Loss

The fat-burning slice of HGH without growth or blood sugar side effects. Similar to AOD-9604.

Fat Loss
5/10
Sentiment
9/10
from $28
Details →

Melanotan II

moderate
Skin & Hair

Darkens skin with less UV exposure. Also affects appetite and libido.

Fat Loss
4/10
Sentiment
8/10
from $25
Details →

IGF-1 LR3

emerging
💪 Muscle Growth🩹 Injury Healing

Long-lasting IGF-1 that drives muscle growth and cell proliferation. Limited human data.

Fat Loss
4/10
Sentiment
6/10
from $60
Details →

AC-262,536

anecdotal
💪 Muscle Growth

SARM with 66% of testosterone's muscle-building power and fewer side effects.

Fat Loss
4/10
Sentiment
8/10
from $40
Details →

DISCONTINUED: Experimental peptide that cuts blood supply to fat cells. Terminated due to kidney toxicity.

Fat Loss
4/10
Sentiment
8/10
from $85
Details →

GHRP-6

moderate
💪 Muscle Growth

Boosts growth hormone and significantly increases appetite.

Fat Loss
3/10
Sentiment
8/10
from $20
Details →
Longevity🧠 Brain & Cognition💪 Muscle Growth

Targets and repairs damaged mitochondria. Boosts cellular energy production.

Fat Loss
3/10
Sentiment
10/10
from $80
Details →
Longevity🧠 Brain & Cognition😴 Sleep

Essential cellular energy molecule. Levels drop ~50% by middle age.

Fat Loss
3/10
Sentiment
9/10
from $75
Details →
💪 Muscle Growth

10x more potent IGF-1 variant with very short duration. Targets local muscle.

Fat Loss
3/10
Sentiment
9/10
from $50
Details →
💪 Muscle Growth🩹 Injury Healing

Long-lasting muscle growth factor released after exercise-induced damage.

Fat Loss
2/10
Sentiment
10/10
from $35
Details →
From our network:Cornerstone Peptide