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peptide

Dihexa

anecdotalResearch Use OnlyOralInjection

Brain peptide originally claimed to be 10 million times more potent than BDNF for forming connections. However, the foundational paper was retracted in April 2025 after confirmed data fabrication. A clinical trial also failed all endpoints. Evidence base is now significantly weakened.


Key facts
Classification
Peptide — Experimental brain peptide for forming new neural connections. Limited safety data.
Primary benefits
Brain & Cognition (5/10) · Longevity (2/10)
Administration
Oral, Injection
Doses studied
10-20 mg oral or 5-10 mg subq daily. Cycle for 4-8 weeks with breaks in between. NOTE: foundational research retracted in 2025 -- consider alternatives like Cerebrolysin or Semax with stronger evidence.
Evidence strength
Anecdotal — 14 peer-reviewed studies
Stacks well with
Semax, Selank, NA-Semax Amidate, SS-31
Legal status
Research Use Only · not prescribable in US
Quick stats
Type
Peptide
Administration
Oral, Injection
Studies referenced
14
Stacks with
6 peptides
Regulatory
Research Use Only
Goal coverage · Dihexa
🧠 Brain & Cognition5/10
Longevity2/10
FIG.1  Modeled goal coverage from reviewed studies. Score out of 10.
Medical oversight strongly recommendedNot safe during pregnancy· 4 contraindications
From our network:Cornerstone Peptide