🧊 Best Peptides for Inflammation

Three-amino-acid anti-inflammatory peptide especially effective for gut inflammation. Go-to for IBD and inflammatory gut issues. Also calms systemic inflammation.

Pre-mixed BPC-157 + TB-500 healing combo. Combines targeted tissue repair with systemic healing, amplifying anti-inflammatory and regenerative effects.

A healing compound from human gastric juice. The most extensively studied repair peptide in animal models, with strong preclinical data for tissue repair, gut restoration, and anti-inflammatory effects. Human clinical data remains limited.

Synthetic Thymosin Beta-4, a protein that drives cell migration and tissue repair. Promotes angiogenesis, reduces inflammation, and supports tissue remodeling body-wide. Popular for injury recovery.

Neuropeptide with powerful anti-inflammatory properties. Widely used in mold illness (CIRS) protocols. Regulates gut and lung inflammation, supports immune balance.

A naturally occurring copper peptide your body already makes. Drives skin rejuvenation, wound healing, and anti-aging by boosting collagen and activating anti-aging genes.

Your body's natural antibiotic peptide. Fights bacteria, viruses, and fungi, breaks up biofilms, and supports wound healing while modulating immune response.

Semi-synthetic polysaccharide (not a peptide) with anti-inflammatory and cartilage-protecting properties. FDA-approved for interstitial cystitis. Widely used for joint health.

Derived from EPO but modified to activate tissue repair without increasing red blood cells. Protects nerves, fights inflammation. Studied for neuropathy and sarcoidosis.

Oral-stable BPC-157 formulation using arginine salt for bioavailability. Delivers peptide directly to the GI tract for localized gut healing without injections.

Longevity peptide that selectively triggers senescent 'zombie cells' to self-destruct while sparing healthy cells. One of the most precise senolytic tools available.

Tightens seals between gut lining cells, directly addressing leaky gut. Developed for celiac disease but useful for gut barrier problems broadly.

28-amino-acid immune peptide from thymus tissue. Strengthens T-cell maturation, boosts natural killer cells, and balances immune response. Tested in 30+ trials, approved in 35+ countries for hepatitis, HIV support, and infections. No serious side effects.

Protective mitochondrial peptide that shields cells from oxidative stress, supports brain cell survival, and protects the heart.

Derived from the thymus gland. Restores immune function and has shown life-extending properties by reactivating the aging immune system.

Engineered to target inner mitochondrial membrane via cardiolipin binding. Stabilizes cristae, improves ATP production, and reduces oxidative stress. FDA-approved for Barth syndrome (as Forzinity) — the first FDA-approved mitochondria-targeted therapy.

Mitochondrial DNA-encoded peptide that activates AMPK, improving insulin sensitivity, fat burning, and mimicking exercise at the cellular level. Stacks well with SS-31 and NAD+.

Cardiovascular bioregulator peptide that supports blood vessel health, strengthens vessel walls, and promotes healthy circulation.

Next-gen triple agonist from Eli Lilly hitting GLP-1, GIP, and glucagon receptors. Phase 2 showed 24.2% weight loss at 48 weeks — highest of any incretin therapy. At low doses, optimizes metabolism without major weight loss.

Enhanced Selank with better stability and bioavailability. Delivers stronger anxiolytic and immune-boosting effects than regular Selank.

Dual GLP-1/glucagon weight loss peptide from Boehringer Ingelheim. The glucagon component adds liver fat reduction, promising for fatty liver disease alongside obesity.

Thymus hormone requiring zinc as a cofactor. Supports proper immune cell development and thymus regeneration. Production declines with age.

Russian anxiolytic peptide working on GABA, serotonin, and enkephalin systems. Eases anxiety without sedation or dependence risk. Also boosts immunity. Decades of clinical use.

Active ingredient in Ozempic/Wegovy. Mimics GLP-1 to signal fullness and slow gastric emptying. STEP trials showed 14.9% weight loss at 68 weeks.

Active ingredient in Mounjaro/Zepbound. Dual GLP-1/GIP agonist — more effective than semaglutide. SURMOUNT-1 showed up to 22.5% weight loss at 72 weeks.

Critical molecule for cellular energy and DNA repair. Levels may drop ~50% by middle age. Activates sirtuin longevity genes and powers PARP DNA repair enzymes. Injectable form bypasses oral absorption issues.

Exercise mimetic that activates endurance pathways, improves mitochondrial function, increases fat burning, and boosts muscle endurance — without actual exercise.

Dual GLP-1/glucagon receptor drug from Innovent Biologics. Strong weight loss and metabolic results. Already approved in China for obesity.

The bonding hormone released during social connection. Promotes trust, empathy, and closeness while reducing anxiety and cortisol.

First-gen GLP-1 drug (Saxenda/Victoza). Less potent than semaglutide but has years of clinical data and established safety profile. Requires daily injection.